一、个人简介、教育和工作经历
魏丹丹,男,安徽寿县人,农业昆虫及害虫防治专业博士学位,导师为王进军教授。任中国昆虫学会第十一届理事会农业昆虫专业委员会委员、中国粮油学会储藏物分会第八届、第九届理事会理事。博士学位论文荣获2014年度重庆市优秀博士学位论文。主要教育和工作经历如下:
2003/09-2007/07,星际网游,星际网游,学士
2007/07-2012/07,星际网游,星际网游,博士(提前攻博)
2011/07-2011/08,澳大利亚昆士兰大学,短期访问学者
2012/07-2014/06,星际网游,星际网游,讲师
2018/12-2019/12,美国加州大学河滨分校,访问学者
2014/07-2021/06,星际网游,星际网游,副教授
2021/07-至今,星际网游,星际网游,教授
二、研究方向与领域
主要从事重要仓储害虫(书虱、豆象)和柑橘害虫(桔小实蝇、柑橘全爪螨、橘蚜等)比较基因组学、抗性的分子遗传学及其微生物防控研究。具体研究方向主要涉及分子种群遗传学,分子标记的开发与应用,裂化线粒体基因组的进化机制与功能优势、核基因与线粒体基因协同表达机制、昆虫抗性与免疫的分子机制等。
三、 主要成果
(一)代表性论文
1. He W, Wei DD, Xu HQ, Yang Y, Miao ZQ, Wang L, Wang JJ*. 2021. Molecular characterization and transcriptional expression analysis of ABC transporter H subfamily genes in the oriental fruit fly. Journal of Economic Entomology, 114: 1298-1309.(共同第一作者)
2. Wei DD, Tu YQ, Guo PY, Wang JJ*. 2021. Characterization of the complete mitochondrial genome of a barklouse, Lepinotus sp. (Psocodea: Trogiomorpha: Trogiidae). Mitochondrial DNA Part B Resources, 6: 1725-1726.
3. Miao ZQ, Tu YQ, Guo PY, He W, Jing TX, Wang JJ, Wei DD*. 2020. Antioxidant enzymes and heat shock protein genes from Liposcelis bostrychophila are involved in stress defense upon heat shock. Insects, 11: 839.
4. Wei DD, He W, Miao ZQ, Tu YQ, Wang L, Dou W, Wang JJ*. 2020. Characterization of esterase genes involving malathion detoxification and establishment of an RNA interference method in Liposcelis bostrychophila. Frontiers in Physiology, 11: 274.
5. Shang F, Niu JZ, Ding BY, Zhang W, Wei DD, Wei D, Jiang HB, Wang JJ. 2020*. The miR-9b microRNA mediates dimorphism and development of wing in aphids. Proceedings of the National Academy of Sciences of the United States of America, 117: 8404-8409.
6. Wei DD, Lang N, Tao Y, He W, Tu YQ, Miao ZQ, Yang L, Wang JJ*. 2019. The mitochondrial genome of the brown citrus aphid Aphis (Toxoptera) citricidus: Insights into the repeat regions in aphids and phylogenetic implications. International Journal of Biological Macromolecules, 136: 531-539.
7. Wei DD, He W, Lang N, Miao ZQ, Xiao LF, Dou W, Wang JJ*. 2019. Recent research status of Bactrocera dorsalis: Insights from resistance mechanisms and population structure. Archives of Insect Biochemistry and Physiology, 102: e21601.
8. Chen EH, Hou QL, Wei DD, Dou W, Liu Z, Yang PJ, Smagghe G, Wang JJ*. 2018. Tyrosine hydroxylase coordinates larval-pupal tanning and immunity in oriental fruit fly (Bactrocera dorsalis). Pest Management Science, 74: 569-578.(共同第一作者)
9. Chen EH, Hou QL, Dou W, Wei DD, Yue Y, Yang RL, Yang PJ, Yu SF, Schutter KD, Smagghe G, Wang JJ*. 2018. Genome-wide annotation of cuticular proteins in the oriental fruit fly (Bactrocera dorsalis), changes during pupariation and expression analysis of CPAP3 protein genes in response to environmental stresses. Insect Biochemistry and Molecular Biology, 97: 53-70.
10. Jing TX, Wu YX, Li T, Wei DD, Smagghe G, Wang JJ*. 2017. Identification and expression profiles of fifteen delta-class glutathione S-transferase genes from a stored-product pest, Liposcelis entomophila (Enderlein) (Psocoptera: Liposcelididae). Comparative Biochemistry and Physiology, Part B, 206: 35-41.
11. Shi Y, Chu Q, Wei DD, Qiu YJ, Shang F, Dou W, Wang JJ*. 2016. The mitochondrial genome of booklouse, Liposcelis sculptilis (Psocoptera: Liposcelididae) and the evolutionary timescale of Liposcelis. Scientific Reports, 6: 30660.
12. Li T, Liu Y, Wei DD, Shang F, Smagghe G, Dou W, Wang JJ*. 2016. Characterization and expression profiles of five possible cytochrome p450 genes from Liposcelis entomophila (Enderlein) (Psocoptera: Liposcelididae). Archives of Insect Biochemistry and Physiology, 92: 259-273.
13. Shang F, Wei DD, Jiang XZ, Wei D, Shen GM, Feng YC, Li T, Wang JJ*. 2015. Reference gene validation for quantitative PCR under various biotic and abiotic stress conditions in Toxoptera citricida (Hemiptera, Aphidiae). Journal of Economic Entomology, 108: 2040-2047.
14. Chen SC, Wei DD, Shao RF, Shi JX, Dou W, Wang JJ*. 2014. Evolution of multipartite mitochondrial genomes in the booklice of the genus Liposcelis (Psocoptera). BMC Genomics, 15: 861. (共同第一作者)
15. Chen SC, Wei DD, Shao RF, Dou W, Wang JJ*. 2014. The complete mitochondrial genome of the booklouse, Liposcelis decolor: insights into gene arrangement and genome organization within the genus Liposcelis. PLoS ONE, 9: e91902. (共同第一作者)
16. Wei DD, Chen EH, Ding TB, Chen SC, Dou W, Wang JJ*. 2013. De Novo assembly, gene annotation, and marker discovery in stored-product pest Liposcelis entomophila (Enderlein) using transcriptome sequences. PLoS ONE, 8(11): e80046.
17. Wei DD, Yuan ML, Wang BJ, Zhou AW, Dou W, Wang JJ*. 2012. Population genetics of two asexually and sexually reproducing psocids species inferred by the analysis of mitochondrial and nuclear DNA sequences. PLoS ONE, 7(3): e33883.
18. Wei DD, Shao R, Yuan ML, Dou W, Barker SC, Wang JJ*. 2012. The multipartite mitochondrial genome of Liposcelis bostrychophila: insights into the evolution of mitochondrial genomes in bilateral animals. PLoS ONE, 7(3): e33973.
19. Wei DD, Yuan ML, Wang ZY, Wang D, Wang BJ, Dou W, Wang JJ*. 2011. Sequence analysis of the ribosomal internal transcribed spacers region in psocids (Psocoptera: Liposcelididae) for phylogenetic inference and species discrimination. Journal of Economic Entomology, 104(5): 1720-1729.
20. Chen EH, Wei DD, Shen GM, Yuan GR, Bai PP, Wang JJ*. 2014. De novo characterization of the Dialeurodes citri transcriptome: mining genes involved in stress resistance and simple sequence repeats (SSRs) discovery. Insect Molecular Biology, 23: 52-66.
21. Jiang XZ, Wei DD, Yang WJ, Dou W, Chen SC, Wang JJ*. 2013. Molecular characterization and alternative splicing of a sodium channel and DSC1 ortholog genes in Liposcelis bostrychophila Badonnel (Psocoptera: Liposcelididae). International Journal of Biological Sciences, 9(9): 989-1003.
22. Chen EH, Wei D, Wei DD, Yuan GR, Wang JJ*. 2013. The effect of dietary restriction on longevity, fecundity, and antioxidant responses in the oriental fruit fly, Bactrocera dorsalis (Hendel) (Diptera: Tephritidae). Journal of Insect Physiology, 59(10): 1008-1016.
23. Yuan ML, Wei DD, Wang BJ, Dou W, Wang JJ*. 2010. The complete mitochondrial genome of the citrus red mite Panonychus citri (Acari: Tetranychidae): high genome rearrangement and extremely truncated tRNAs. BMC genomics, 11: 597.
24. Yuan ML, Wei DD, Zhang K, Gao YZ, Liu YH, Wang BJ, Wang JJ*. 2010. Genetic diversity and population structure of the citrus red mite, Panonychus citri (Acari: Tetranychidae), in China based on mitochondrial COI gene sequences. Journal of Economic Entomology, 103(6): 2204-2213.
25. Wei D, Li HM, Yang WJ, Wei DD, Dou W, Huang Y, Wang JJ*. 2015. Transcriptome profiling of the testis reveals genes involved in spermatogenesis and marker discovery in the oriental fruit fly, Bactrocera dorsalis. Insect Molecular Biology, 24: 41-57. (SCI)
26. Bai PP, Xie YF, Shen GM, Wei DD, Wang JJ*. 2014. Phenoloxidase and its zymogen are required for the larval-pupal transition in Bactrocera dorsalis (Diptera: Tephritidae). Journal of Insect Physiology, 71: 137-146. (SCI)
27. 魏丹丹, 苗泽青, 涂艳清, 何旺, 王磊, 豆威, 王进军*. 2019. 我国城市昆虫学研究的回顾与展望. 应用昆虫学报, 56: 1193-1205.
28. 景田兴, 郎宁, 豆威, 魏丹丹, 王进军*. 2017. 书虱代谢抗性研究进展. 中国粮油学报, 32: 191-196.
29. 魏丹丹, 刘燕, 杜洋, 李刚, 李婷, 袁明龙, 王进军*. 2016. 柑橘全爪螨微卫星位点鉴定与信息分析. 中国农业科学, 49: 282-293.
30. 魏丹丹, 邵韧夫, 陈世春, 王进军*. 2014. 啮总目昆虫的线粒体基因组多样性及系统发育研究进展. 昆虫学报, 57: 483-494.
31. 魏丹丹, 石俊霞, 张夏瑄, 陈世春, 魏冬, 王进军*. 2014. 基于转录组数据的桔小实蝇微卫星微点信息分析. 应用生态学报, 25: 1799-1805.
32. 魏丹丹, 袁明龙, 王保军, 朱礼明, 王进军*. 2011. 两种书虱微卫星富集文库的构建及比较. 生态学报, 31(15): 4182-4189.
33. 蒋玄赵, 魏丹丹, 申光茂, 豆威, 王进军*. 2012. 桔小实蝇电压门控钠离子通道基因cDNA克隆及其生物信息学分析. 中国农业科学, 45(19): 3996-4003.
(二)发明专利
1. 魏丹丹, 郎宁, 苗泽青, 肖林帆,王进军。发明专利。一种嗜卷书虱SOD1基因的RNA干扰方法。专利号: 201810045338.7。授权时间: 2021.07。
2. 魏丹丹, 陶勇, 胥财源, 王进军。实用新型专利。一种快速采集仓储害虫书虱的吸虫器。专利号: 201820541222.8。授权时间: 2019.02。
3. 王进军,魏丹丹,豆威,王梓英,袁明龙。发明专利。一种基于多重PCR技术快速鉴定常见仓储书虱的方法,专利授权号:201110120037。授权时间: 2013.03。
4. 王进军,袁明龙,豆威,魏丹丹,王保军。发明专利。一种柑橘全爪螨微卫星富集文库的构建方法,专利授权号:201110063902。授权时间: 2013.05。
5. 王进军,魏冬,豆威,魏丹丹,夹福先。实用新型专利。一种实蝇类害虫单头饲养及虫卵收集装置,专利授权号:201220529146。授权时间: 2013.05。
(三)科研项目
1. 热激转录因子Hsfs调控HSP70s表达介导嗜卷书虱药剂耐受性的分子机制,国家自然科学基金面上项目(32272528),2023-2026,主持;
2. 嗜卷书虱裂化线粒体基因组功能适应性机制研究,国家自然科学基金面上项目(31972276),2020-2023,主持;
3. 橘小实蝇等入侵种免疫识别的分子基础与防控靶点研究,国家重点研发项目(2022YFC2601002),2020-2025,主持;
4. 钻蛀性果树害虫绿色防控技术研发及集成与应用,国家重点研发项目(2019YFD1002102),2019-2022,子课题主持;
5. 入侵生物致害与风险分析的分子标记与控制靶点,国家重点研发项目(2016YFC1200605),2016-2018,子课题主持;
6. 嗜卷书虱种群遗传结构及分化机制研究,国家自然科学基金青年项目(31301667),2014-2016,主持;
7. 桔小实蝇C型凝集素基因的鉴定及其功能研究,重庆市自然科学基金面上项目(cstc2020jcyj-msxmX0494),2020-2023,主持;
8. 嗜卷书虱线粒体基因组裂化机制及其转录组学研究,重庆市前沿与应用基础研究项目(cstc2015jcyjA0254),2016-2018,主持。
(四)出版教材与专著
1. Wei DD, Miao ZQ, Tu YQ, Guo PY, Wang JJ. 2023. Molecular biology of stored product psocids. In: Athanassiou, C. G., Nayak, M. K. (Eds.), Psocids as Global Pests of Stored Products. CABI, Wallingford, UK, pp. 46-64.
2. 魏丹丹, 荣霞 主编. 2019. 普通昆虫学实验实习指导. 西南师范大学出版社. 重庆;
3. 参编. 2020. 植物害虫检疫学. 科学出版社. 北京.
4. 参编. 2021. 柑橘病虫害绿色防控彩色图谱. 中国农业出版社. 北京.
(五)获奖情况
1. 仓储害虫二氧化碳气调胁迫应答的毒理学机制, 贵州省科学技术奖自然科学奖二等奖, 2021, 排名第二.
四、联系方式
E-mail:weidandande@163.com;wdd@swu.edu.cn;联系电话:023-68250653
通讯地址:星际网游农业科学研究院901室,重庆市北碚区天生路2号,400716